Improved Intensity-Based Label-Free Quantification via Proximity-Based Intensity Normalization (PIN)
نویسندگان
چکیده
منابع مشابه
Improved Intensity-Based Label-Free Quantification via Proximity-Based Intensity Normalization (PIN)
Researchers are increasingly turning to label-free MS1 intensity-based quantification strategies within HPLC-ESI-MS/MS workflows to reveal biological variation at the molecule level. Unfortunately, HPLC-ESI-MS/MS workflows using these strategies produce results with poor repeatability and reproducibility, primarily due to systematic bias and complex variability. While current global normalizati...
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ژورنال
عنوان ژورنال: Journal of Proteome Research
سال: 2014
ISSN: 1535-3893,1535-3907
DOI: 10.1021/pr400866r